Now showing items 21-40 of 95

    • Brucella evolution and taxonomy 

      Cloeckaertb, Axel; Moriyon, Ignacio; Moreno, Edgardo (Elsevier Science B.V, 2002)
      The genus Brucella contains alpha-Proteobacteria adapted to intracellular life within cells of a variety of mammals. Controversy has arisen concerning Brucella internal taxonomy, and it has been proposed that the DNA–DNA ...
    • Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution 

      Suárez-Esquivel, Marcela; Baker, Kate; Ruiz-Villalobos, Nazareth; Hernandez-Mora, Gabriela; BARQUERO-CALVO, ELIAS; González-Barrientos, Rocío; Castillo-Zeledón, Amanda; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Cloeckaert, Axel; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
      Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...
    • Brucella genomics: macro and micro evolution 

      Guzman-Verri, Caterina; Suárez-Esquivel, Marcela; Chaves Olarte, Esteban; Moreno, Edgardo (MDPI AG, 2020-10-20)
      Brucella organisms are responsible for one of the most widespread bacterial zoonoses, named brucellosis. The disease affects several species of animals, including humans. One of the most intriguing aspects of the brucellae ...
    • Brucella melitensis: a nasty bug with hidden credentials for virulence 

      Moreno, Edgardo; Moriyón, Ignacio (The National Academy of Sciences, 2002-01-08)
      On September 23, 1905, a cargo carrying 60 goats from Malta arrived in New York. The herd was kept in quarantine because of several deaths that occurred during the journey. Crewmen, an agent from the U.S. Bureau of Animal ...
    • Brucella neotomae infection in humans, Costa Rica 

      BARQUERO-CALVO, ELIAS; Baker, Kate S.; Amuy, Ernesto; Chaves-Olarte, Esteban; Thomson, Nicholas R.; Moreno, Edgardo; Guzman-Verri, Caterina; Suárez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Víquez-Ruiz, Eunice; Rojas-Campos, Norman; Oviedo-Sánchez, Gerardo (Emerging Infectious Diseases, 2017-06)
      Several species of Brucella are known to be zoonotic, but B. neotomae infection has been thought to be limited to wood rats. In 2008 and 2011, however, B. neotomae was isolated from cerebrospinal fluid of 2 men with ...
    • Brucella sp. sequence‑type 27 associated with abortion in dwarf sperm whale Kogia sima 

      Hernández-Mora, Gabriela; González-Barrientos, Rocío; Víquez‑Ruíz, Eunice; Palacios Alfaro, Jose David; Bettoni‑Rodríguez, Gianmarco; Gendre, Marlène; Vincent, Charline; Roca‑Monge, Karol; Ruiz-Villalobos, Nazareth; Suárez-Esquivel, Marcela; Cordero‑Chavarría, Minor; Chaves-Olarte, Esteban; Thomson, Nicholas R.; BARQUERO-CALVO, ELIAS; Moreno, Edgardo; Guzman-Verri, Caterina (Springer Link, 2021-05-18)
      A dwarf sperm whale Kogia sima stranded alive along the Central Pacifc Coast of Costa Rica. The whale, handled by tourists and local inhabitants, was weak, had buoyancy difculties, and eventually aborted and died, showing ...
    • Brucella spp. en el hato ovino costarricense 

      Barrantes Granados, Osvaldo (Universidad Nacional, Costa Rica, 2015-03-12)
      La brucelosis en ovinos es causada por Brucella melitensis, B. abortus, y B. ovis, provocando principalmente en el caso de las dos primeras especies, problemas en la reproducción de las hembras y en el caso de B. ovis, ...
    • Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells 

      Moreno, Edgardo; Martirosyan, Anna; Pérez-Gutierrez, Camino; Banchereau, Romain; Dutartre, Helene; Lecine, Patrick; Dullaers, Melissa; MELLO, Marielle; salcedo, suzana; Muller, Alexandre; Leserman, Lee; Levy, Yves; Zurawski, Gerard; Zurawski, Sandy; Moriyon, Ignacio; Klechevsky, Eynav; Banchereau, Jacques; Oh, SangKon; Gorvel, Jean-Pierre (PLoS Pathogens, 2012-11-15)
      Bacterial cyclic glucans are glucose polymers that concentrate within the periplasm of alpha-proteobacteria. These molecules are necessary to maintain the homeostasis of the cell envelope by contributing to the osmolarity ...
    • Brucella-Salmonella lipopolysaccharide chimeras are less permeable to hydrophobic probes and more sensitive to cationic peptides and EDTA than are their native Brucella sp. counterparts 

      Freer, Enrique; Moriyón, Ignacio; Pizarro Cerda, Javier; Weintraub, Andrej; Gorvel, Jean Pierre; Moreno, Edgardo (American Society for Microbiology, 1996-08-12)
      A rough (R) Brucella abortus 45/20 mutant was more sensitive to the bactericidal activity of polymyxin B and lactoferricin B than was its smooth (S) counterpart but considerably more resistant than Salmonella montevideo. ...
    • Brucellosis caused by the wood rat pathogen Brucella Neotomae: two case reports 

      Arnuy, Ernesto; Rojas, Norman; Villalobos-Vindas, Juan M.; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Moreno, Edgardo (Journal of Medical Case Reports, 2017-12-19)
      Background: Brucellosis is a chronic bacterial disease caused by members of the genus Brucella. Among the classical species stands Brucella neotomae, until now, a pathogen limited to wood rats. However, we have identified ...
    • Brucellosis in Central America 

      Moreno, Edgardo (Elsevier Science B.V, 2002)
      Brucellosis is a disease of domestic animals and humans in Central America (CA). Bovine and swine brucellosis caused by Brucella abortus and Brucella suis, respectively, have been identified in all CA countries, while ovine ...
    • Brucellosis in mammals of Costa Rica: an epidemiological survey 

      Hernández-Mora, Gabriela; Bonilla-Montoya, Roberto; Barrantes-Granados, Osvaldo; Esquivel-Suárez, Andrea; Montero-Caballero, Danilo; Fallas-Monge, Zeanne; Palacios Alfaro, Jose David; Baldi, Mario; Campos, Elena; Chanto, Grettel; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Romero-Zúñiga, Juan José; Moreno, Edgardo (PLOS ONE, 2017-08-09)
      La brucelosis ha sido una enfermedad endémica del ganado y los seres humanos en Costa Rica desde principios del siglo XX. Sin embargo, no se ha reportado brucelosis en ovejas, cabras, cerdos, búfalos de agua, caballos y ...
    • Brucellosis in mammals of Costa Rica: An epidemiological survey 

      Hernández Mora, Gabriela; Bonilla Montoya, Roberto; Barrantes Granados, Osvaldo; Esquivel Suárez, Andrea; Montero Caballero, Danilo; González Barrientos, Rocío; Fallas Monge, Zeanne; Palacios Alfaro, José David; Campos, Elena; Chanto, Grettel; Chacón Díaz, Carlos; BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; ROMERO-ZUÑIGA, JUAN JOSÉ; Moreno, Edgardo; Baldi, Mario (PLOS ONE, 2017-08-09)
      Brucellosis has been an endemic disease of cattle and humans in Costa Rica since the beginning of XX century. However, brucellosis in sheep, goats, pigs, water buffaloes, horses and cetaceans, has not been reported in ...
    • BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence 

      Manterola, Lorea; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; BARQUERO-CALVO, ELIAS; de Miguel, María-Jesús; Moriyon, Ignacio; Grillo, María-Jesús; López-Goñi, Ignacio; Moreno, Edgardo (American Society for Microbiology, 2007-07-30)
      The Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ...
    • Canine brucellosis in Costa Rica reveals widespread Brucella canis infection and the recent introduction of foreign strains 

      Foster, Jeffrey; Guzman-Verri, Caterina; Suárez Esquivel, Marcela; Ruiz Villalobos, Nazareth; Hidalgo Jara, Warren; Chacon Díaz, Carlos; Zúniga Pereira, Ana Mariel; Masís Mora, Mario; Fernández Fernández, Ericka; Hernández Mora, Gabriela; BARQUERO-CALVO, ELIAS; Chaves Olarte, Esteban; Thomson, Nicholas R.; Moreno, Edgardo (Elsevier, 2021-04-16)
      Brucellosis is a prevalent disease in Costa Rica (CR), with an increasing number of human infections. Close to half of homes in CR have one or more dogs, corresponding to ∼1.4 million canines, most of them in the Central ...
    • Caracterización de la diversidad genética de Brucella ceti aisladas en la costa del Pacífico de Costa Rica, mediante secuenciación de nueve genes seleccionados 

      Piche-Ovares, María Marta (Universidad Nacional, Costa Rica, 2013)
      Trece aislamientos bacterianos provenientes de delfines Stenella coeruleoalba encallados en la costa Pacífica de Costa Rica, fueron sometidos a caracterización bioquímica e identificados como Brucella ceti. Los mismos ...
    • Caracterización de la región promotora del gen omp25 de Brucella abortus. 

      Castillo Zeledón, Amanda (Universidad Nacional, Costa Rica, 2010)
      La brucelosis es una enfermedad zoonótica, producida por bacterias del género Brucella. Muchos de los mecanismos que utiliza esta bacteria para invadir y replicarse en las células no se comprenden. Sin embargo, las ...
    • Caracterización fenotípica de aislamientos de Brucella sp. obtenidos a partir de murciélagos (Desmodus rotundus) en Piedras Blancas, Puntarenas, Costa Rica 

      Hidalgo Montealegre, Daniela (Universidad Nacional, Costa Rica, 2024)
      Brucella es un género de bacterias responsable de causar brucelosis, una enfermedad zoonótica distribuida en el mundo. Las brucelas causan problemas reproductivos en animales domésticos y silvestres e infecciones ...
    • Characterization of Brucella abortus and Brucella melitensis native haptens as outer membrane O-type polysaccharides independent from the smooth lipopolysaccharide 

      Aragón, V; Díaz Porras, Rafael; Moriyón, Ignacio; Moreno, Edgardo (American Society for Microbiology, 1996)
      Brucella native haptens (NHs) extracted with hot water from smooth (S)- type B. abortus and B. melitensis were purified to high levels of serological activity and compared with the polysaccharide obtained by acid hydrolysis ...
    • Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts 

      Lapaque, Nicolas; Forquet, Frédérique; Chastellier, Chantal de; Mishal, Zohair; Jolly, Gilles; Moriyon, Ignacio; Heuser, John E.; Hai-Tao, He; Gorvel, Jean Pierre; Moreno, Edgardo (Blackwell Science, 2005-09-28)
      The lipopolysaccharides (LPS) of intracellular Proteobacteria such as Brucella, Chlamydia, Legionella and Rickettsia, have properties distinct from enterobacterial LPSs. These properties include deficient LPS induction of ...