Now showing items 1-6 of 6

    • An in vivo model to study the anti-malaric capacity of plant extracts 

      Chinchilla, Misael; Guerrero., OIga; Abarca, Gabriela; Barrios, , Mariano; Castro, Oscar (Universidad de Costa Rica, 1998)
      An in vivo model to study the antimalaric effect of plant extracts is described. White mice (25-30g body weight) are treated subcutaneously with 0.6ml of the diluted extract starting seven days before P. berghei infection; ...
    • Evaluación farmacológica y química de Stachytarpheta jamaicensis (Verbenaceae) 

      Melita Rodríguez, Sergia; Castro, Oscar (Universidad de Costa Rica, 1996)
      Afier intraperitoneal administration of gradual aqueous doses obtained from Stachytarpheta jamaicensis leaves, the following effects were observed in rats: a reduction of motor activity and the alarm reaction, ataxia, ...
    • Evaluación química y biológica del efecto de extractos de plantas contra Plasmodium berghei 

      Castro, Oscar; Barrios, Mariano; Chinchilla, Misael; Guerrero, OIga (Universidad de Costa Rica, 1996)
      Extracts from thirteen species of plants were evaluated by "in vivo" antimalarial test against Plasmodium berghei effects. Significant activities were observed in the ethyl acetate and aqueous extracts, elaborated of ...
    • Iridoids from the aerial parts of Verbena littoralis (Verbenaceae) 

      Castro-Gamboa, Ian; Castro, Oscar (Elsevier, 2004)
      The iridoids, 6S-hydroxy-8S-methyl-4-methylene-hexahydro-cyclopenta[c]pyran-3-one and 6S,9S-dihydroxy-8S-methyl-4- methylene-hexahydro-cyclopenta[c]pyran-3-one, were isolated from the aerial parts of Verbena littoralis. ...
    • Maxonine, a novel alkaloid from Simira maxonii 

      Hasbun, Carlos P.; Calderon, Minor; Castro, Oscar; Gacs Baitz, Eszter; Delle Monache, Giuliano; Delle Monache, Franco (Elsevier, 1989)
      A novel alkaloid, maxonine, with an indole-pyrido-naphthyridine skeleton, has been isolated from . Its structure was elucidated on the basis of 2D NMR spectral data. A novel alkaloid, maxonine (1), with an indolepyrido-n ...
    • Neutralización del efceto hemorrágico inducido por veneno Bothrops asper (Serpentes: Viperidae) por extractos de las plantas tropicales 

      Castro, Oscar; Gutiérrez, José María; Barrios, Mariano; Castro, Ian; Romero, Marjorie; Umaña, Eduardo (Universidad Nacional (Costa Rica), 1999)
      Organic extracts representing 48 species included in 30 families of Costa Rican tropical plants were evaluated for their hability to neutralize hemorrhagic acfivity lnduced by the venom of the snake Bothrops aspero Abioassay ...