Browsing Facultad de Ciencias de la Salud by Author "Lapaque, Nicolas"
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Brucella abortus lipopolysaccharide in murine peritoneal macrophages acts as a down-regulator of T cell activation
Forestier, Claire; Deleuil, Fabienne; Lapaque, Nicolas; Gorvel, Jean Pierre; Moreno, Edgardo (The American Association of Immunologists, Inc., 2000)Macrophages play a central role in host immune responses against pathogens by acting as both professional phagocytic cells and as fully competent APCs. We report here that the LPS from the facultative intracellular ... -
Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts
Lapaque, Nicolas; Forquet, Frédérique; Chastellier, Chantal de; Mishal, Zohair; Jolly, Gilles; Moriyon, Ignacio; Heuser, John E.; Hai-Tao, He; Gorvel, Jean Pierre; Moreno, Edgardo (Blackwell Science, 2005-09-28)The lipopolysaccharides (LPS) of intracellular Proteobacteria such as Brucella, Chlamydia, Legionella and Rickettsia, have properties distinct from enterobacterial LPSs. These properties include deficient LPS induction of ...