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Pathology of striped dolphins (Stenella coeruleoalba) infected with Brucella ceti
(Elsevier Ltd, 2009-10-14)
Seventeen striped dolphins (Stenella coeruleoalba) displaying swimming disorders compatible with neurological syndromes were investigated for Brucella infection. Sixteen dolphins had meningoencephalomyelitis. Serum antibody ...
Serological diagnosis of brucella infections in odontocetes
(American Society for Microbiology, 2009-04-15)
Brucella ceti causes disease in Odontoceti. The absence of control serum collections and the diversity of
cetaceans have hampered the standardization of serological tests for the diagnosis of cetacean brucellosis. Without ...
Neurobrucellosis in stranded dolphins, Costa Rica
(Universidad Nacional, Costa Rica, 2008-09)
Ten striped dolphins, Stenella coeruleoalba, stranded along the Costa Rican Pacifi c coast, had meningoencephalitis and antibodies against Brucella spp. Brucella ceti was isolated from cerebrospinal fl uid of 6 dolphins ...
Intracellular adaptation of Brucella abortus
(Universidad Nacional, Costa Rica, 2009-03)
Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially ...
Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection
(PLOS ONE, 2007-07-18)
Background. To unravel the strategy by which Brucella abortus establishes chronic infections, we explored its early interaction with innate immunity. Methodology/Principal Findings. Brucella did not induce proinflammatory ...
BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence
(American Society for Microbiology, 2007-07-30)
The Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ...
Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking
(Blackwell Science, 2002-10-04)
Brucella abortus is an intracellular pathogen that relies on unconventional virulence factors to infect hosts. In non-professional phagocytes, Rho GTPasesactivation by the Escherichia coli cytotoxic necrotiz ing factor ...
R-Ras Glucosylation and transient RhoA activation determine the cytopathic effect produced by Toxin B variants from Toxin A-negative strains of clostridium difficile
(American Society for Biochemistry and Molecular Biology, 2003-03-07)
Clostridium difficile induces antibiotic-associated diarrhea through the production of toxin A and toxin B;
the former toxin has been assumed to be responsible for the symptoms of the disease. Several toxin A-negative ...
GTPases of the Rho subfamily are required for Brucella abortus internalization in nonprofessional phagocytes
(The American Society for Biochemistry and Molecular Biology, Inc., 2001-11-30)
Members of the genus Brucella are intracellular -Proteobacteria
responsible for brucellosis, a chronic disease
of humans and animals. Little is known about Brucella
virulence mechanisms, but the abilities of these ...
In vivo proteolytic degradation of the Escherichia coli acyltransferase HlyC
(The American Society for Biochemistry and Molecular Biology, 2001-05-18)
Escherichia coli hemolysin (HlyA) is the prototype toxin of a major family of exoproteins produced by Gram-negative bacteria known as “repeats in toxins.” Only fatty acid-acylated HlyA molecules at residues Lys564 and ...