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MyD88, but not Toll-Like receptors 4 and 2, Is required for efficient clearance of Brucella abortus
(American Society for Microbiology, 2005-08)
It is not clear how the host initially recognizes and responds to infection by gram-negative pathogenic
Brucella spp. It was previously shown (D. S. Weiss, B. Raupach, K. Takeda, S. Akira, and A. Zychlinsky, J.
Immunol. ...
Brucella melitensis: a nasty bug with hidden credentials for virulence
(The National Academy of Sciences, 2002-01-08)
On September 23, 1905, a cargo carrying 60 goats from Malta arrived in New York. The herd was kept in quarantine because of several deaths that occurred during the journey. Crewmen, an agent from the U.S. Bureau of Animal ...
Facing the human and animal Brucellosis conundrums: the forgotten lessons
(MDPI, 2022-04-30)
Brucellosis is a major zoonotic disease caused by Brucella species. Historically, the disease
received over fifty names until it was recognized as a single entity, illustrating its protean manifesta-
tions and intricacies, ...
Genome evolution within the alpha Proteobacteria: why do some bacteria not possess plasmids and others exhibit more than one diferent chromosome?
(Elsevier, 1998)
Animal intracellular Proteobacteria of the alpha subclass without plasmids and containing one or more chromosomes are
phylogenetically entwined with opportunistic, plant-associated, chemoautotrophic and photosynthetic ...
Virulent Brucella nosferati infecting Desmodus rotundus has emerging potential due to the broad foraging range of its bat host for humans and wild and domestic animals
(American Society for Microbiology, 2023-07-05)
Desmodus rotundus, vampire bats, transmit dangerous infections, and
brucellosis is a hazardous zoonotic disease, two adversities that coexist in the subtropical
and tropical areas of the American continent. Here, we ...
Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation
(Frontiers Media S.A, 2023-05-10)
Brucella abortus is a zoonotic pathogen whose virulence depends on its ability to survive intracellularly at the endoplasmic reticulum derived compartment. The two-component system BvrR/BvrS (BvrRS) is essential for ...
The Brucella abortus two-component system response regulator BvrR binds to three DNA regulatory boxes in the upstream region of omp25
(Frontiers Media S.A, 2023-09-14)
Brucella abortus is a facultative extracellular-intracellular bacterial zoonotic pathogen worldwide. It is also a major cause of abortion in bovines, generating economic losses. The two-component regulatory system BvrR/BvrS ...
If You're Not Confused, You're Not Paying Attention: Ochrobactrum Is Not Brucella
(American Society for Microbiology, 2023-07-03)
Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living, ...
A sensor histidine kinase from a plant-endosymbiont bacterium restores the virulence of a mammalian intracellular pathogen
(Elsevier, 2023-11-08)
Alphaproteobacteria include organisms living in close association with plants or animals. This interaction relies partly on orthologous two-component regulatory systems (TCS), with sensor and regulator proteins modulating ...
Brucella intracellular life: from invasion to intracellular replication
(Elsevier, 2002)
Brucella organisms are pathogens that ultimate goal is to propagate in their preferred niche, the cell. Upon cell contact the bacteria is internalized via receptor molecules by activating small GTPases of the Rho subfamily ...