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Depletion of complement enhances the clearance of Brucella abortus in mice
(American Society for Microbiology, 2018-08-06)
Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. Since ...
N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils
(Universidad Nacional, Costa Rica, 2016-06)
Brucella abortus is an intracellular pathogen of monocytes, macrophages, dendritic cells, and placental trophoblasts. This bacterium causes a chronic disease in bovines and in humans. In these hosts, the bacterium also ...
An electrophoretic study on phospholipase A2 isoenzymes in the venoms of Central American crotaline snakes
(Elsevier, 1992)
The number and isoelectric points of phospholipase A2 isoenzymes were studied in the venoms of 12 Central American crotaline snakes of the genera Bothrops, Crotalus, Lachesis and Agkistrodon. The study was carried out by ...
Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region
(Elsevier, 2005)
A short peptide derived from the C-terminal region of Bothrops asper myotoxin II, a Lys49 phospholipase A2 (PLA2), was previously found to reproduce the bactericidal activity of its parent molecule. In this study, a panel ...
Bactericidal and Antiendotoxic Properties of Short Cationic Peptides Derived from a Snake Venom Lys49 Phospholipase A2
(American Society for Microbiology, 2005-04)
The activities of short synthetic, nonhemolytic peptides derived from the C-terminal region of myotoxin 11, a catalytically inactive phospholipase A(2) homologue present in the venom of the snake Bothrops asper, have been ...
Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom Synthetic Lys49 myotoxin II-(115−129)-peptide identifies its bactericidal region
(FEBS, 1998)
Mammalian group-II phospholipases A2 (PLA2) of inflammatory fluids display bactericidal properties, which are dependent on their enzymatic activity. This study shows that myotoxins II (Lys49) and III (Asp49), two group-II ...
Detection of proteins antigenically related to Bothrops asper myotoxin in crotaline snake venoms
(Pergamon Press, 1987-03-05)
H. Loxtoxre, E, Moatnvo and J . M. GurtEsaez . Detation of proteins antigenically rdated to
Bothrops riper myotoxin in crotaline snake venoms. Tadcon 25, 947 -953, 1987 . - The presence
of componrnts antigenically related ...
Índices bibliométricos y revistas de ‘corriente central’: implicaciones para el desarrollo de las ciencias naturales en Costa Rica
(Universidad de Costa Rica, 2015-05)
Una característica asociada con el
surgimiento de la ciencia moderna, en los
siglos XVI y XVII, fue el establecimiento
de una rica dinámica ‘socializadora’ del
conocimiento mediante reuniones periódicas
entre científicos, ...
Computational biology in Costa Rica: the role of a small country in the global context of bioinformatics
(PLoS Computational Biology, 2008-03-14)
The successful development of high throughput methods for
DNA sequencing, transcriptomics, proteomics, and other –omics,
has contributed to the emergence of novel possibilities for the
examination of complex biological ...
Virulent Brucella nosferati infecting Desmodus rotundus has emerging potential due to the broad foraging range of its bat host for humans and wild and domestic animals
(American Society for Microbiology, 2023-07-05)
Desmodus rotundus, vampire bats, transmit dangerous infections, and
brucellosis is a hazardous zoonotic disease, two adversities that coexist in the subtropical
and tropical areas of the American continent. Here, we ...