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In vivo animal models confrm an increased virulence potential and pathogenicity of the NAP1/RT027/ST01 genotype within the Clostridium difcile MLST Clade 2
(BioMed Central, 2020-09-22)
Background: Based on MLST analyses the global population of C. difcile is distributed in eight clades, of which
Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types ...
A bvrR/bvrS Non-Polar Brucella abortus Mutant Confirms the Role of the Two-Component System BvrR/BvrS in Virulence and Membrane Integrity
(MDPI, 2023-08-05)
Brucella abortus is a bacterial pathogen causing bovine brucellosis worldwide. This facultative extracellular–intracellular pathogen can be transmitted to humans, leading to a zoonotic disease.
The disease remains a public ...