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Novel genotype of Ehrlichia canis detected in samples of human blood bank donors in Costa Rica
(Ticks and Tick- borne Diseases, 2017-09-23)
This study focuses on the detection and identification of DNA and antibodies to Ehrlichia spp. in samples of blood bank donors in Costa Rica using molecular and serological techniques. Presence of Ehrlichia canis was ...
Persistence of Brucella abortus in the bone marrow of infected mice
(Journal of Immunology Research, 2018-12-03)
Brucellosis is a zoonotic bacterial infection that may persist for long periods causing relapses in antibiotic-treated patients. The ability of Brucella to develop chronic infections is linked to their capacity to invade ...
What have we learned from brucellosis in the mouse model?
(Veterinary Research, 2012)
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by
practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(PLoS Pathogens, 2012-05-10)
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
Alertan ante derretimiento de glaciales
(Escuela de Medicina Veterinaria, 2020-03)
A medida que el cambio climático provocado por el ser humano derrite los glaciares en todo el mundo, podrían resurgir microorganismos desconocidos por la ciencia.
Si bien el coronavirus ha puesto en alerta a la población ...
A Sinorhizobium meliloti and Agrobacterium tumefaciens ExoR ortholog is not crucial for Brucella abortus virulence
(PLOS ONE, 2021-08-13)
Brucella is a facultative extracellular-intracellular pathogen that belongs to the Alphaproteo-
bacteria class. Precise sensing of environmental changes and a proper response mediated
by a gene expression regulatory ...
The regulon of Brucella abortus two- component system BvrR/BvrS reveals the coordination of metabolic pathways required for intracellular life
(PLOS ONE, 2022-09-21)
Brucella abortus is a facultative intracellular pathogen causing a severe zoonotic disease
worldwide. The two-component regulatory system (TCS) BvrR/BvrS of B. abortus is con-
served in members of the Alphaproteobacteria ...
Estudiar para prevenir : estudios científicos señalan que los mapaches podrían ser reservorios de enfermedades transmisibles a los humanos (zoonóticas), que incluyen virus, bacterias y parásitos de diferentes tipos.
(Universidad Nacional, Costa Rica, 2016-05)
Dada la constante presencia de mapaches en la Gran Área Metropolitana de Costa Rica (GAM) y la posible transmisión de agentes infecciosos responsables de causar enfermedad en humanos, un equipo de investigadores de la ...
A bvrR/bvrS Non-Polar Brucella abortus Mutant Confirms the Role of the Two-Component System BvrR/BvrS in Virulence and Membrane Integrity
(MDPI, 2023-08-05)
Brucella abortus is a bacterial pathogen causing bovine brucellosis worldwide. This facultative extracellular–intracellular pathogen can be transmitted to humans, leading to a zoonotic disease.
The disease remains a public ...
Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation
(Frontiers Media S.A, 2023-05-10)
Brucella abortus is a zoonotic pathogen whose virulence depends on its ability to survive intracellularly at the endoplasmic reticulum derived compartment. The two-component system BvrR/BvrS (BvrRS) is essential for ...