Browsing by Author "Altamirano-Silva, Pamela"

Now showing items 1-8 of 8

    • A bvrR/bvrS Non-Polar Brucella abortus Mutant Confirms the Role of the Two-Component System BvrR/BvrS in Virulence and Membrane Integrity 

      Rivas-Solano, Olga; Núñez-Montero, Kattia; Altamirano-Silva, Pamela; Ruiz-Villalobos, Nazareth; BARQUERO-CALVO, ELIAS; Moreno, Edgardo; Chaves-Olarte, Esteban; Guzman-Verri, Caterina (MDPI, 2023-08-05)
      Brucella abortus is a bacterial pathogen causing bovine brucellosis worldwide. This facultative extracellular–intracellular pathogen can be transmitted to humans, leading to a zoonotic disease. The disease remains a public ...

    • A Sinorhizobium meliloti and Agrobacterium tumefaciens ExoR ortholog is not crucial for Brucella abortus virulence 

      Castillo Zeledon, Amanda; Ruiz-Villalobos, Nazareth; Altamirano-Silva, Pamela; Chacón-Díaz, Carlos; BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Guzman-Verri, Caterina (PLOS ONE, 2021-08-13)
      Brucella is a facultative extracellular-intracellular pathogen that belongs to the Alphaproteo- bacteria class. Precise sensing of environmental changes and a proper response mediated by a gene expression regulatory ...

    • Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts 

      Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Altamirano-Silva, Pamela; González-Espinoza, Gabriela; Medina, María-Concepción; Alfaro-Alarcón, Alejandro; Bouza-Mora, Laura; Jiménez-Rojas, César; Wong, Melissa; BARQUERO-CALVO, ELIAS; Rojas, Norman; Moreno, Edgardo; Chaves-Olarte, Esteban (Infection and Immunity, 2015-09-29)
      Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ...

    • If You're Not Confused, You're Not Paying Attention: Ochrobactrum Is Not Brucella 

      Moreno, Edgardo; Middlebrook, Earl A.; Altamirano-Silva, Pamela; Al Dahouk, Sascha; Araj, George F.; Arce-Gorvel, Vilma; Arenas-Gamboa, Ángela; Ariza, Javier; BARQUERO-CALVO, ELIAS; Battelli, Giorgio; Bertu, Wilson J.; Blasco, José María; Bosilkovsk, Mile; Cadmus, Simeon; Caswell, Clayton C.; Celli, Jean; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Comerci, Diego J.; Conde-Álvarez, Raquel; Cook, Elizabeth; Cravero, Silvio; Dadar, Maryam; De Boelle, Xavier; De Massis, Fabrizio; Díaz, Ramón; Escobar, Gabriela I.; Fernández-Lago, Luis; Ficht, Thomas A.; Foster, Jeffrey T.; Garin-Bastuji, Bruno; Godfroid, Jacques; Gorvel, Jean-Pierre; Güler, Leyla; Erdenlig-Gürbilek, Sevil; Gusi, Amayel M.; Guzman-Verri, Caterina; Hai, Jiang; Hernández-Mora, Gabriela; Iriarte, Maite; Jacob, Nestor R.; Keriel, Anne; Khames, Maamar; Köhler, Stephan; Letesson, Jean-Jacques; Loperena-Barber, Maite; López-Goñi, Ignacio; McGiven, John; Melzer, Falk; Mora-Cartin, Ricardo; Moran-Gilad, Jacob; Muñoz, Pilar M.; Neubauer, Heinrich; O'Callaghan, David; Ocholi, Reuben; Oñate, Ángel; Pandey, Piyush; Pappas, Georgios; Pembroke, J. Tony; Roop, Martin; Ruiz-Villalobos, Nazareth; Ryan, Michael P.; Salvador-Bescós, Miriam; Sangari, Félix J.; de Lima Santos, Renato; Seimenis, Aristarchos; Splitter, Gary; Suárez-Esquivel, Marcela; Tabbaa, Darem; Trangoni, Marcos David; Tsolis, Renee M.; Vizcaíno, Nieves; Wareth, Gamal; . Welburn, Susan C; Whatmore, Adrian; Zúñiga-Ripa, Amaia; Moriyónq, Ignacio (American Society for Microbiology, 2023-07-03)
      Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living, ...

    • Neutrophils as Trojan Horse vehicles for Brucella abortus macrophage infection 

      Gutiérrez-Jiménez, Cristina; Mora-Cartín, Ricardo; Altamirano-Silva, Pamela; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Moreno, Edgardo; BARQUERO-CALVO, ELIAS (Universidad Nacional, Costa Rica, 2019-05-07)
      Brucella abortus is a stealthy intracellular bacterial pathogen of animals and humans. This bacterium promotes the premature cell death of neutrophils (PMN) and resists the killing action of these leukocytes. B. abortus-infected ...

    • Phenotypes controlled by the Brucella abortus two component system BvrR/BvrS are differentially impacted by BvrR phosphorylation 

      Altamirano-Silva, Pamela; Meza-Torres, Jazmín; Zúñiga-Pereira, Ana Mariel; Zamora-Jaen, Sigrid; Pietrosemoli, Natalia; Cantos, Gabriela; Peltier, Johann; Pizarro-Cerdá, Javier; Moreno, Edgardo; Chacón-Díaz, Carlos; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (Frontiers Media S.A, 2023-05-10)
      Brucella abortus is a zoonotic pathogen whose virulence depends on its ability to survive intracellularly at the endoplasmic reticulum derived compartment. The two-component system BvrR/BvrS (BvrRS) is essential for ...

    • Purification of intracellular bacteria: isolation of viable Brucella abortus from host cells 

      Chaves-Olarte, Esteban; Altamirano-Silva, Pamela; Guzman-Verri, Caterina; Moreno, Edgardo (Springer Science, Business Media Nueva York, 2014, 2014)
      The pathogenesis of brucellosis depends on the ability of bacteria from the genus Brucella to invade and replicate within animal cells. To understand the molecular pathways used by Brucella spp. to reach its intracellular ...

    • The two-component system BvrR/BvrS regulates the expression of the Type IV secretion system VirB in Brucella abortus 

      Martínez-Núñez, Carola; Altamirano-Silva, Pamela; Alvarado-Guillén, Francisco; Moreno, Edgardo; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (American Society for Microbiology, 2010-11)
      The pathogenesis of Brucella is related to the ability to multiply intracellularly, an event controlled by the two-component system BvrR/BvrS (TCS BvrRS) and the type IV secretion machinery VirB (T4SS VirB). We have ...