Now showing items 1-3 of 3

    • Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern 

      Palacios-Chaves, Leyre; Conde-Álvarez, Raquel; Gil-Ramírez, Yolanda; Zúñiga-Ripa, Amaia; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Arce-Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; de Miguel, María-Jesús; Grilló, María-Jesús; Moriyon, Ignacio; Iriarte, Maite (PLoS One, 2011-01-07)
      The brucellae are a-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Moreno, Edgardo; BARQUERO-CALVO, ELIAS; Conde-Álvarez, Raquel; Arce-Gorvel, Vilma; Iriarte, Maite; Manček Keber, Mateja; Palacios-Chaves, Leyre; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Martirosyan, Anna; von Bargen, Kristine; Grilló, María-Jesús; Jerala, Roman; Brandenburg, Klaus ; Llobet, Enrique; Bengoechea, José A.; Moriyon, Ignacio; Gorvel, Jean-Pierre (PLoS Pathogens, 2012-05-10)
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
    • What have we learned from brucellosis in the mouse model? 

      Moreno, Edgardo; Grilló, María-Jesús; Blasco, José María; Gorvel, Jean-Pierre; Moriyon, Ignacio (Veterinary Research, 2012)
      Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...