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Orthotopic bone regeneration within 3D printed bioceramic scaffolds with region-dependent porosity gradients in an equine model
(WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2020-03-03)
The clinical translation of three-dimensionally printed bioceramic scaffolds with tailored architectures holds great promise toward the regeneration of bone to heal critical-size defects. Herein, the long-term in vivo ...
Long-term in vivo performance of low-temperature 3D-printed bioceramics in an equine model
(American Chemical Society, 2020-01-31)
Bone has great self-healing capacity, but above a certain critical size, bone defects will not heal spontaneously, requiring intervention to achieve full healing. Among the synthetic calcium phosphate (CaP) bone replacement ...
The use of a cartilage decellularized matrix scaffold for the repair of osteochondral defects: the importance of long-term studies in a large animal model
(Osteoarthritis Research Society International. Published by Elsevier, 2016-08-21)
Objective: To investigate the effect of decellularized cartilage-derived matrix (CDM) scaffolds, by itself and as a composite scaffold with a calcium phosphate (CaP) base, for the repair of osteochondral defects.
It was ...
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica
(Universidad Nacional, Costa Rica, 2019)
The paper provides results published or to be published of long-term in vivo equine studies to evaluate techniques of possible regenerative matrices of cartilage and bone, by means of cell-free implants or ...
Fixation of hydrogel constructs for cartilage repair in the equine model: a challenging issue
(Tissue Engineering, 2017-11-07)
Objective: To report on the experiences with the use of commercial and autologous fibrin glue (AFG) and of an alternative method based on a 3D-printed polycaprolactone (PCL) anchor for the fixation of hydrogel-based scaffolds ...