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Purification of intracellular bacteria: isolation of viable Brucella abortus from host cells
(Springer Science, Business Media Nueva York, 2014, 2014)
The pathogenesis of brucellosis depends on the ability of bacteria from the genus Brucella to invade and
replicate within animal cells. To understand the molecular pathways used by Brucella spp. to reach its
intracellular ...
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
(PLoS One, 2011-01-07)
The brucellae are a-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated ...
A Sinorhizobium meliloti and Agrobacterium tumefaciens ExoR ortholog is not crucial for Brucella abortus virulence
(PLOS ONE, 2021-08-13)
Brucella is a facultative extracellular-intracellular pathogen that belongs to the Alphaproteo-
bacteria class. Precise sensing of environmental changes and a proper response mediated
by a gene expression regulatory ...
Platelet depletion does not alter the course of Brucella abortus infection in vivo
(Elsevier, 2022-02-23)
Brucellosis is a bacterial disease of animals and a zoonotic infection. Thrombocytopenia is a common outcome in
long-lasting brucellosis in humans. Likewise, ex vivo experiments have shown that platelets may play a role ...
Determination of streptomycin and doxycycline using LC/MS towards an effective treatment against an experimental Brucella abortus infection in mice
(Elsevier B.V, 2022-02-25)
Herein we described a versatile liquid chromatographic method for detection and quantification of the total
levels of two antimicrobials [i.e., streptomycin (STM) and doxycycline (DOX)], in mice plasma and selected
tissues, ...
Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes
(American Society for Microbiology, 1988-09-01)
Brucella abortus is an intracellular pathogen that replicates within a membrane-bounded compartment. In
this study, we have examined the intracellular pathway of the virulent B. abortus strain 2308 (S2308) and the
attenuated ...
Brucella-Salmonella lipopolysaccharide chimeras are less permeable to hydrophobic probes and more sensitive to cationic peptides and EDTA than are their native Brucella sp. counterparts
(American Society for Microbiology, 1996-08-12)
A rough (R) Brucella abortus 45/20 mutant was more sensitive to the bactericidal activity of polymyxin B and lactoferricin B than was its smooth (S) counterpart but considerably more resistant than Salmonella montevideo. ...
Characterization of Brucella abortus and Brucella melitensis native haptens as outer membrane O-type polysaccharides independent from the smooth lipopolysaccharide
(American Society for Microbiology, 1996)
Brucella native haptens (NHs) extracted with hot water from smooth (S)- type B. abortus and B. melitensis were purified to high levels of serological activity and compared with the polysaccharide obtained by acid hydrolysis ...
Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts
(Blackwell Science, 2005-09-28)
The lipopolysaccharides (LPS) of intracellular Proteobacteria such as Brucella, Chlamydia, Legionella and Rickettsia, have properties distinct from enterobacterial LPSs. These properties include deficient LPS induction of ...
Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis
(PLOS Neglected Tropical Diseases, 2020-04-14)
Brucellosis, caused by Brucella abortus, is a major disease of cattle and humans worldwide distributed. Eradication and control of the disease has been difficult in Central and South America, Central Asia, the Mediterranean ...