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Novel genotype of Ehrlichia canis detected in samples of human blood bank donors in Costa Rica
(Ticks and Tick- borne Diseases, 2017-09-23)
This study focuses on the detection and identification of DNA and antibodies to Ehrlichia spp. in samples of blood bank donors in Costa Rica using molecular and serological techniques. Presence of Ehrlichia canis was ...
Isolation and identification of Arcobacter species from Costa Rican poultry production and retail sources
(Journal of food protection, 2017-04-03)
Arcobacter is a gram-negative rod recognized as a potential food- and waterborne pathogen; nevertheless, little is known about the effects of this pathogen on human and animal health. Although Arcobacter species are commonly ...
Brucella abortus induces the premature death of human neutrophils through the action of Its lipopolysaccharide
(PLoS Pathogens, 2015-05-06)
Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus ...
Neutrophils dampen adaptive immunity in Brucellosis
(American Society For Microbiology, 2019-04-23)
Brucella organisms are intracellular stealth pathogens of animals and humans. The bacteria overcome the assault of innate immunity at early stages of an infection. Removal of polymorphonuclear neutrophils (PMNs) at the ...
Neutrophils as Trojan Horse vehicles for Brucella abortus macrophage infection
(Universidad Nacional, Costa Rica, 2019-05-07)
Brucella abortus is a stealthy intracellular bacterial pathogen of animals and humans. This bacterium promotes the premature cell death of neutrophils (PMN) and resists the killing action of these leukocytes. B. abortus-infected ...
Persistence of Brucella abortus in the bone marrow of infected mice
(Journal of Immunology Research, 2018-12-03)
Brucellosis is a zoonotic bacterial infection that may persist for long periods causing relapses in antibiotic-treated patients. The ability of Brucella to develop chronic infections is linked to their capacity to invade ...
What have we learned from brucellosis in the mouse model?
(Veterinary Research, 2012)
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by
practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(PLoS Pathogens, 2012-05-10)
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
Identification and antimicrobial susceptibility of obligate anaerobic bacteria from clinical samples of animal origin
(Anaerobe, 2015-09-14)
The etiology of veterinary infectious diseases has been the focus of considerable research, yet relatively little is known about the causative agents of anaerobic infections. Susceptibility studies have documented the ...
Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells
(PLoS Pathogens, 2012-11-15)
Bacterial cyclic glucans are glucose polymers that concentrate within the periplasm of alpha-proteobacteria. These molecules are necessary to maintain the homeostasis of the cell envelope by contributing to the osmolarity ...