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Prenatal mancozeb exposure, excess manganese, and neurodevelopment at 1 year of age in the Infants' Environmental Health (ISA) study
(Environmental Health Perspectives, 2018-05-29)
BACKGROUND: Although growing evidence suggests that early-life excess manganese (Mn) impairs neurodevelopment, data on the neurodevelopmental effects of mancozeb, a fungicide containing Mn, and its main metabolite ...
Caregiving and infants' neurodevelopment in rural Costa Rica: Results from the Infants’ Environmental Health Study (ISA)
(Elsevier, 2019-09)
Early caregiving is one of the strongest influences on children's development, and among the most significant modifiable environmental factor. The aim of this study was to explore the association between quality of ...
Maternal blood and hair manganese concentrations, fetal growth, and length of gestation in the ISA cohort in Costa Rica
(Environmental Research, 2015-01)
Background: Animal studies have shown that both deficiency and excess manganese (Mn) may result in decreased fetal size and weight, but human studies have reported inconsistent results. Methods: We examined the association ...
Caregiving and infants' neurodevelopment in rural Costa Rica: results from the Infants’ Environmental Health Study (ISA)
(Elsevier, 2019-06-05)
Early caregiving is one of the strongest influences on children’s development, and among the most significant modifiable environmental factor. The aim of this study was to explore the association between quality of ...
Prenatal and postnatal manganese teeth levels and neurodevelopment at 7, 9, and 10.5 years in the CHAMACOS cohort
(Elsevier, 2015-11)
Background: Numerous cross-sectional studies of school-age children have observed that exposure to manganese (Mn) adversely affects neurodevelopment. However, few prospective studies have looked at the effects of both ...
Exposure to common-use pesticides, manganese, lead, and thyroidfunction among pregnant women from the Infants' EnvironmentalHealth (ISA) study, Costa Rica
(Elsevier, 2021-10-28)
Background:Pesticides and metals may disrupt thyroid function, which is key to fetal brain development.Objectives:To evaluate if current-use pesticide exposures, lead and excess manganese alter free thyroxine (FT4),freet ...