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Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus
(PLoS Pathogens, 2013-02-14)
Polymorphonuclear neutrophils (PMNs) are the first line of defense against microbial pathogens. In addition to their role in innate immunity, PMNs may also regulate events related to adaptive immunity. To investigate the ...
Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich
(American Society for Microbiology., 2018-01-16)
Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...
Analysis of the association between density of Helicobacter spp and gastric lesions in dogs
(American Journal of Veterinary Research, 2017-12)
OBJECTIVE
To evaluate the correlation between the density of native gastric Helicobacter spp and the presence of gastric lesions in dogs.
ANIMALS
80 dogs of various breeds, sexes, and ages.
PROCEDURES
Gastroscopic and ...
Combined electrokinetic manipulations of pathogenic bacterial samples in low-cost fabricated dielectrophoretic devices
(AIP Advances, 2019-11-13)
A low-cost fabrication method of microfluidic devices with micrometer-sized constrictions used for electrodeless dielectrophoresis (eDEP)
is demonstrated here. A structure on a commercial printed circuit board (PCB) ...
The differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens
(PLOS ONE, 2009-06-16)
Background: During evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. However, some a-Proteobacteria are stealthy intracellular pathogens not readily detected by this system. ...
Intracellular adaptation of Brucella abortus
(Universidad Nacional, Costa Rica, 2009-03)
Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially ...
Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking
(Blackwell Science, 2002-10-04)
Brucella abortus is an intracellular pathogen that relies on unconventional virulence factors to infect hosts. In non-professional phagocytes, Rho GTPasesactivation by the Escherichia coli cytotoxic necrotiz ing factor ...
GTPases of the Rho subfamily are required for Brucella abortus internalization in nonprofessional phagocytes
(The American Society for Biochemistry and Molecular Biology, Inc., 2001-11-30)
Members of the genus Brucella are intracellular -Proteobacteria
responsible for brucellosis, a chronic disease
of humans and animals. Little is known about Brucella
virulence mechanisms, but the abilities of these ...
In vivo proteolytic degradation of the Escherichia coli acyltransferase HlyC
(The American Society for Biochemistry and Molecular Biology, 2001-05-18)
Escherichia coli hemolysin (HlyA) is the prototype toxin of a major family of exoproteins produced by Gram-negative bacteria known as “repeats in toxins.” Only fatty acid-acylated HlyA molecules at residues Lys564 and ...
Purification of intracellular bacteria: isolation of viable Brucella abortus from host cells
(Springer Science, Business Media Nueva York, 2014, 2014)
The pathogenesis of brucellosis depends on the ability of bacteria from the genus Brucella to invade and
replicate within animal cells. To understand the molecular pathways used by Brucella spp. to reach its
intracellular ...