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Regulation of Brucella virulence by the two-component system BvrR/BvrS
(Elsevier B.V., 2002-12-20)
The Brucella BvrR/BvrS two-component regulatory system is highly similar to the regulatory and sensory proteins of Sinorhizobium and Agrobacterium necessary for endosymbiosis and pathogenicity in plants, and very similar ...
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum
(The Rockefeller University Press, 2003-01-18)
The intracellular pathogen Brucella is the causative agent of brucellosis, a worldwide zoonosis
that affects mammals, including humans. Essential to Brucella virulence is its ability to survive and
replicate inside host ...
Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes
(American Society for Microbiology, 1988-09-01)
Brucella abortus is an intracellular pathogen that replicates within a membrane-bounded compartment. In
this study, we have examined the intracellular pathway of the virulent B. abortus strain 2308 (S2308) and the
attenuated ...
Brucella abortus lipopolysaccharide in murine peritoneal macrophages acts as a down-regulator of T cell activation
(The American Association of Immunologists, Inc., 2000)
Macrophages play a central role in host immune responses against pathogens by acting as both professional phagocytic cells and
as fully competent APCs. We report here that the LPS from the facultative intracellular ...
Brucella-Salmonella lipopolysaccharide chimeras are less permeable to hydrophobic probes and more sensitive to cationic peptides and EDTA than are their native Brucella sp. counterparts
(American Society for Microbiology, 1996-08-12)
A rough (R) Brucella abortus 45/20 mutant was more sensitive to the bactericidal activity of polymyxin B and lactoferricin B than was its smooth (S) counterpart but considerably more resistant than Salmonella montevideo. ...
Brucellosis in mammals of Costa Rica: An epidemiological survey
(PLOS ONE, 2017-08-09)
Brucellosis has been an endemic disease of cattle and humans in Costa Rica since the
beginning of XX century. However, brucellosis in sheep, goats, pigs, water buffaloes, horses
and cetaceans, has not been reported in ...
Pathological Studies and Postmortem Computed Tomography of Dolphins with Meningoencephalomyelitis and Osteoarthritis Caused by Brucella ceti
(MDPI, 2022-05-09)
Cetacean neurobrucellosis is a common cause of strandings in Costa Rica diagnosed by
serology, bacteriology, and histopathology. Pathological studies were performed on 18 dolphins.
Twelve were scanned by postmortem ...
Characterization of Brucella abortus and Brucella melitensis native haptens as outer membrane O-type polysaccharides independent from the smooth lipopolysaccharide
(American Society for Microbiology, 1996)
Brucella native haptens (NHs) extracted with hot water from smooth (S)- type B. abortus and B. melitensis were purified to high levels of serological activity and compared with the polysaccharide obtained by acid hydrolysis ...
Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts
(Blackwell Science, 2005-09-28)
The lipopolysaccharides (LPS) of intracellular Proteobacteria such as Brucella, Chlamydia, Legionella and Rickettsia, have properties distinct from enterobacterial LPSs. These properties include deficient LPS induction of ...
Comparison of the antibody response in adult cattle against different epitopes of Brucella abortus lipopolysaccharide
(Blackwell, 2001)
The comparison of serological responses in a sample of adult, vaccinated and held-infected bovines with Brucella abortus is reported. Indirect enzyme immunoassav (EIA) titration curves and Western blotting tests for ...